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Anastrozol ist ein Medikament, das hauptsächlich in der Behandlung von hormonempfindlichem Brustkrebs eingesetzt wird. Es gehört zur Gruppe der Aromatasehemmer und wirkt, indem es die Umwandlung von Androgenen in Östrogen blockiert. Dieser Mechanismus reduziert die Östrogenspiegel im Körper, was für Frauen mit bestimmten Arten von Brustkrebs von entscheidender Bedeutung ist, da viele Tumore auf Östrogen angewiesen sind, um zu wachsen und sich zu verbreiten.
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Anastrozol hemmt das Enzym Aromatase, das für die Umwandlung von Androgenen in Östrogene verantwortlich ist. Dies führt zu einer Senkung des Östrogenspiegels im Körper. Die Hauptwirkungen sind:
Anastrozol wird vor allem in folgenden Situationen eingesetzt:
Wie jedes Medikament kann auch Anastrozol Nebenwirkungen verursachen. Zu den häufigsten gehören:
Es ist wichtig, mit Ihrem Arzt über mögliche Nebenwirkungen und deren Management zu sprechen, bevor Sie mit einer Anastrozol-Behandlung beginnen.
Insgesamt ist Anastrozol ein wichtiges Medikament im Kampf gegen Brustkrebs, insbesondere bei Frauen in der Menopause. Seine Wirkung als Aromatasehemmer hält den Östrogenspiegel niedrig und kann so das Wachstum von Tumoren effektiv hemmen.